May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport By similarity.Friedli M., Gene 320:31-40(2003).Strippoli P., Mamm. Genome 13:456-462(2002)
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human CLIC6.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport By similarity.
Friedli M., Gene 320:31-40(2003). Strippoli P., Mamm. Genome 13:456-462(2002)
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total CLIC6 protein.
Subcellular Location
Cytoplasm, Cell membrane, Single-pass membrane protein
May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport (By similarity).
Protein Families
Chloride channel CLIC family
Tissue Specificity
Expressed in brain, placenta, pancreas and liver.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.