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Home / Antibodies

CHST6 Antibody

SKU : BHA10558302

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA033577
Alternative Names	Carbohydrate sulfotransferase 6; EC 2.8.2.-; N-acetylglucosamine 6-O-sulfotransferase 5; GlcNAc6ST-5; Corneal N-acetylglucosamine-6-O-sulfotransferase
Categories	Primary Antibodies
Clonality	polyclonal
Description	Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures.Akama T.O., Nat. Genet. 26:237-241(2000).Hemmerich S., Glycobiology 11:75-87(2001).Bartes A., Biochem. Biophys. Res. Commun. 282:928-933(2001).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human CHST6.
Involvement In Disease	Macular dystrophy, corneal (MCD)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures. Akama T.O., Nat. Genet. 26:237-241(2000). Hemmerich S., Glycobiology 11:75-87(2001). Bartes A., Biochem. Biophys. Res. Commun. 282:928-933(2001).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total CHST6 protein.
Subcellular Location	Golgi apparatus membrane, Single-pass type II membrane protein

Uniprot	Q9GZX3
Database Links	HGNC:6938 OMIM:217800 KEGG:hsa:4166 STRING:9606.ENSP00000328983 UniGene:Hs.655622
Function	Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures.
Protein Families	Sulfotransferase 1 family, Gal/GlcNAc/GalNAc subfamily
Tissue Specificity	Expressed in cornea. Mainly expressed in brain. Also expressed in spinal cord and trachea.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IF

Description

ELISA ; IF, IF ; ELISA

Dilution

IF	1:100-1:500

Tested Application

ELISA,IF;IF:1:100-1:500

Datasheet
ELISA Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558302	CSB-PA033577	100ul	$297		Add to Cart

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