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Home / Antibodies

CEP164 Antibody

SKU : BHA10563372

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA892491LA01HU
Alternative Names	Centrosomal protein of 164 kDa (Cep164), CEP164, KIAA1052 NPHP15
Categories	Primary Antibodies
Clonality	polyclonal
Immunogen	Recombinant Human Centrosomal protein of 164 kDa protein (1-112AA)
Involvement In Disease	Nephronophthisis 15 (NPHP15)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Relevance	Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole, Nucleus

Uniprot	Q9UPV0
Database Links	HGNC:29182 OMIM:614845 KEGG:hsa:22897 STRING:9606.ENSP00000278935 UniGene:Hs.504009
Function	Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1.
Research Area	Epigenetics and Nuclear Signaling
Tissue Specificity	Expressed in several cell lines.

Form	Liquid
Purification	>95%, Protein G purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Description	IHC ; ELISA
Tested Application	ELISA, IHC; Recommended dilution: IHC:1:500-1:1000

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10563372	CSB-PA892491LA01HU	100ug	$299		Add to Cart
BHA10563372	CSB-PA892491LA01HU	50ug	$166		Add to Cart

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