C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages.Kinoshita S., Proc. Natl. Acad. Sci. U.S.A. 89:1473-1476(1992).Cleutjens C.B., Genomics 16:520-523(1993).Wang J.-M., Nucleic Acids Res. 34:217-231(2006).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human CEBPE.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages.
Kinoshita S., Proc. Natl. Acad. Sci. U.S.A. 89:1473-1476(1992). Cleutjens C.B., Genomics 16:520-523(1993). Wang J.-M., Nucleic Acids Res. 34:217-231(2006).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total CEBPE protein.