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CAND1 Antibody, HRP conjugated

SKU : BHA10563775

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA774815LB01HU
Alternative Names	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1), CAND1, KIAA0829 TIP120 TIP120A
Categories	Primary Antibodies
Clonality	polyclonal
Immunogen	Recombinant Human Cullin-associated NEDD8-dissociated protein 1 protein (1150-1230AA)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Relevance	Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. The exchange activity of CAND1 is coupled with cycles of neddylation conjugation: in the deneddylated state, cullin-binding CAND1 binds CUL1-RBX1, increasing dissociation of the SCF complex and promoting exchange of the F-box protein. Probably plays a similar role in other cullin-RING E3 ubiquitin ligase complexes.
Subcellular Location	Cytoplasm, Nucleus

Uniprot	Q86VP6
Database Links	HGNC:30688 OMIM:607727 KEGG:hsa:55832 STRING:9606.ENSP00000299218 UniGene:Hs.546407
Function	Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. The exchange activity of CAND1 is coupled with cycles of neddylation conjugation
Protein Families	CAND family
Research Area	Epigenetics and Nuclear Signaling

Form	Liquid
Purification	>95%, Protein G purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Description	ELISA
Tested Application	ELISA

Datasheet
ELISA Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10563775	CSB-PA774815LB01HU	100ug	$299		Add to Cart
BHA10563775	CSB-PA774815LB01HU	50ug	$166		Add to Cart

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