Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.Kaisho T., Proc. Natl. Acad. Sci. U.S.A. 91:5325-5329(1994).Kalnine N., Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.Hillier L.W., Nature 434:724-731(2005).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human BST1.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.
Kaisho T., Proc. Natl. Acad. Sci. U.S.A. 91:5325-5329(1994). Kalnine N., Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. Hillier L.W., Nature 434:724-731(2005).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total BST1 protein.
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.
Protein Families
ADP-ribosyl cyclase family
Tissue Specificity
Widely expressed.
Weight
29,326 Da
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.