Bone morphogenetic protein 8A [Precursor]; BMP-8A;
Antigen
BMP8A
Categories
Primary Antibodies
Clonality
polyclonal
Description
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis By similarity. Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT.Onishi M., Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.Gregory S.G., Nature 441:315-321(2006).
Host
Rabbit
Immunogen
Synthesized peptide derived from C-terminal of Human BMP8A.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis By similarity. Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT.
Onishi M., Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. Gregory S.G., Nature 441:315-321(2006).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total BMP8A protein.
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT.