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Home / Antibodies

BCAS2 Antibody

SKU : BHA10558284

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA446952
Alternative Names	Pre-mRNA-splicing factor SPF27; Spliceosome-associated protein SPF 27; Breast carcinoma-amplified sequence 2; DNA amplified in mammary carcinoma 1 protein; BCAS2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.Neubauer G., Nat. Genet. 20:46-50(1998).Nagasaki K., Cancer Lett. 140:219-226(1999).Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human BCAS2.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Neubauer G., Nat. Genet. 20:46-50(1998). Nagasaki K., Cancer Lett. 140:219-226(1999). Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total BCAS2 protein.
Subcellular Location	Nucleus, nucleolus

Uniprot	O75934
Database Links	HGNC:975 OMIM:605783 KEGG:hsa:10286 STRING:9606.ENSP00000358554 UniGene:Hs.22960
Function	Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Protein Families	SPF27 family
Tissue Specificity	Ubiquitously expressed.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558284	CSB-PA446952	100ul	$297		Add to Cart

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