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Home / Primary Antibodies

BAP1 Antibody / BRCA1-Associated Protein 1 (V7371)

SKU : BHA17116072

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NSJ Bioreagents

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Mfr.No.	V7371, V7371-20UG, V7371-100UG
Clonality	Monoclonal
Description	The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, Uveal melanoma and cutaneous melanoma.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host	Mouse
Immunogen Region	A portion of amino acids 191-326 from the human protein was used as the immunogen for the BAP1 antibody.
Isotype	IgG2c,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Nuclear, cytoplasmic

Uniprot	Q92560
Clone No	BAP1/2432

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the BAP1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	ELISA
Dilution	ELISA (order BSA/sodium azide-free format for coating)

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17116072-1	V7371-20UG	20ug	$219		Add to Cart
BHA17116072-2	V7371-100UG	100ug	$499		Add to Cart

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