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Home / Antibodies

B4GALT1 Antibody

SKU : BHA10558273

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA195029
Alternative Names	b4Gal-T1; B4GALT1; B4GT1; Beta-1; 4-galactosyltransferase 1
Categories	Primary Antibodies
Clonality	polyclonal
Description	The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix.Masri K.A., Biochem. Biophys. Res. Commun. 157:657-663(1988).Watzele G., Nucleic Acids Res. 18:7174-7174(1990).Mengle-Gaw L., Biochem. Biophys. Res. Commun. 176:1269-1276(1991).
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human B4GALT1.
Involvement In Disease	Congenital disorder of glycosylation 2D (CDG2D)
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix. Masri K.A., Biochem. Biophys. Res. Commun. 157:657-663(1988). Watzele G., Nucleic Acids Res. 18:7174-7174(1990). Mengle-Gaw L., Biochem. Biophys. Res. Commun. 176:1269-1276(1991).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total B4GALT1protein.
Subcellular Location	Isoform Long: Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein, Cell membrane, Single-pass type II membrane protein, Cell surface, Cell projection, filopodium, Note=Found in trans cisternae of Golgi but is mainly localized at the plasma membrane (PubMed:1714903), B4GALT1 cell surface expression is regulated by UBE2Q1 (By similarity), SUBCELLULAR LOCATION: Isoform Short: Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein, Note=Found in trans cisternae of Golgi, SUBCELLULAR LOCATION: Processed beta-14-galactosyltransferase 1: Secreted

Uniprot	P15291
Database Links	HGNC:924 OMIM:137060 KEGG:hsa:2683 STRING:9606.ENSP00000369055 UniGene:Hs.272011
Function	The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.; FUNCTION
Protein Families	Glycosyltransferase 7 family
Tissue Specificity	Ubiquitously expressed, but at very low levels in fetal and adult brain.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558273	CSB-PA195029	100ul	$297		Add to Cart

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