Vacuolar proton pump subunit C 2; V-ATPase subunit C 2; ATP6V1C2;
Categories
Primary Antibodies
Clonality
polyclonal
Description
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.Smith A.N., Gene 297:169-177(2002).Hillier L.W., Nature 434:724-731(2005).The MGC Project Team, Genome Res. 14:2121-2127(2004).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human ATP6V1C2.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Smith A.N., Gene 297:169-177(2002). Hillier L.W., Nature 434:724-731(2005). The MGC Project Team, Genome Res. 14:2121-2127(2004).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ATP6V1C2 protein.
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.