ATP synthase subunit s; mitochondrial [Precursor]; ATP synthase-coupling factor B; Mitochondrial ATP synthase regulatory component factor B; ATP5S
Antigen
ATP5S
Categories
Primary Antibodies
Clonality
polyclonal
Description
Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H+ conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway By similarity.Belogrudov G.I., J. Biol. Chem. 277:6097-6103(2002).Ota T., Nat. Genet. 36:40-45(2004).Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human ATP5S.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H+ conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway By similarity.
Belogrudov G.I., J. Biol. Chem. 277:6097-6103(2002). Ota T., Nat. Genet. 36:40-45(2004). Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ATP5S protein.
Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway (By similarity).
Protein Families
ATP synthase subunit s family
Weight
14,667 Da
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.