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Home / Antibodies

Atp1a1 (Ab-23) Antibody

SKU : BHA10559695

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA779386
Alternative Names	A1A1; AT1A1; ATPase; Na+/K+ transporting; alpha 1 polypeptide
Categories	Primary Antibodies
Clonality	polyclonal
Description	This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.Shull G.E., Biochemistry 25:8125-8132(1986).Hara Y., J. Biochem. 102:43-58(1987).Herrera V.L.M., J. Cell Biol. 105:1855-1865(1987).
Host	Rabbit
Immunogen	Synthesized non-phosphopeptide derived from Human ATP1α1/Na+K+ ATPase1 around the phosphorylation site of serine 23 (K-K-S(p)-K-K).
Raised In	Rabbit
Reactivity	Human, Rat
Regulatory	RUO
Relevance	This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Shull G.E., Biochemistry 25:8125-8132(1986). Hara Y., J. Biochem. 102:43-58(1987). Herrera V.L.M., J. Cell Biol. 105:1855-1865(1987).
Species	Rattus Norvegicus (Rat)
Specificity	The antibody detects endogenous levels of total ATP1α1/Na+K+ ATPase1 protein.
Subcellular Location	Cell membrane, sarcolemma, Multi-pass membrane protein

Uniprot	P06685
Gene Id	24211
Database Links	KEGG:rno:24211 STRING:10116.ENSRNOP00000045650 UniGene:Rn.217534
Function	This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Pathway	cAMP signaling pathway Cardiac muscle contraction Th17 cell differentiation cGMP-PKG signaling pathway
Protein Families	Cation transport ATPase (P-type) (TC 3.A.3) family, Type IIC subfamily
Weight	113,054 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559695	CSB-PA779386	100ul	$297		Add to Cart

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