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Home / Antibodies

ATN1 Antibody

SKU : BHA10558257

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA048957
Alternative Names	ATN1; Atrophin-1; Dentatorubral-pallidoluysian atrophy protein; DRPL;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional corepressor. Recruits NR2E1 to repress transcription. Promotes vascular smooth cell (VSMC) migration and orientation By similarity. Corepressor of MTG8 transcriptional repression. Has some intrinsic repression activity which is independent of the number of poly-Asn (polyQ) repeats.Nagafuchi S., Nat. Genet. 8:177-182(1994).Onodera O., Am. J. Hum. Genet. 57:1050-1060(1995).Margolis R.L., Brain Res. Mol. Brain Res. 36:219-226(1996).
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human ATN1.
Involvement In Disease	Dentatorubral-pallidoluysian atrophy (DRPLA)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Transcriptional corepressor. Recruits NR2E1 to repress transcription. Promotes vascular smooth cell (VSMC) migration and orientation By similarity. Corepressor of MTG8 transcriptional repression. Has some intrinsic repression activity which is independent of the number of poly-Asn (polyQ) repeats. Nagafuchi S., Nat. Genet. 8:177-182(1994). Onodera O., Am. J. Hum. Genet. 57:1050-1060(1995). Margolis R.L., Brain Res. Mol. Brain Res. 36:219-226(1996).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total ATN1 protein.
Subcellular Location	Nucleus, Cytoplasm, perinuclear region, Cell junction

Uniprot	P54259
Gene Id	1822
Database Links	HGNC:3033 OMIM:125370 KEGG:hsa:1822 STRING:9606.ENSP00000349076 UniGene:Hs.143766
Function	Transcriptional corepressor. Recruits NR2E1 to repress transcription. Promotes vascular smooth cell (VSMC) migration and orientation (By similarity). Corepressor of MTG8 transcriptional repression. Has some intrinsic repression activity which is independent of the number of poly-Asn (polyQ) repeats.
Tissue Specificity	Widely expressed in various tissues including heart, lung, kidney, ovary, testis, prostate, placenta, skeletal Low levels in the liver, thymus and leukocytes. In the adult brain, broadly expressed in amygdala, caudate nucleus, corpus callosum, hippocampus
Weight	125,414 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558257	CSB-PA048957	100ul	$297		Add to Cart

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