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Home / Primary Antibodies

ARX Antibody

SKU : BHA10558797

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA059506
Alternative Names	aristaless related homeobox; Aristaless-related homeobox; aristaless-related homeobox; X-linked; ARX
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate.Ohira R.H., Mol. Genet. Metab. 77:179-188(2002) [PubMed: 12359145].Turner G., Am. J. Med. Genet. 112:405-411(2002) [PubMed: 12376946].Bienvenu T., Hum. Mol. Genet. 11:981-991(2002) [PubMed: 11971879].
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human ARX.
Involvement In Disease	Lissencephaly, X-linked 2 (LISX2); Epileptic encephalopathy, early infantile, 1 (EIEE1); Partington syndrome (PRTS); Mental retardation, X-linked, ARX-related (MRXARX); Agenesis of the corpus callosum, with abnormal genitalia (ACCAG)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate. Ohira R.H., Mol. Genet. Metab. 77:179-188(2002) [PubMed: 12359145]. Turner G., Am. J. Med. Genet. 112:405-411(2002) [PubMed: 12376946]. Bienvenu T., Hum. Mol. Genet. 11:981-991(2002) [PubMed: 11971879].
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total ARX protein.
Subcellular Location	Nucleus

Uniprot	Q96QS3
Gene Id	170302
Database Links	HGNC:18060 OMIM:300004 KEGG:hsa:170302 STRING:9606.ENSP00000368332 UniGene:Hs.300304
Function	Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate.
Protein Families	Paired homeobox family, Bicoid subfamily
Tissue Specificity	Expressed predominantly in fetal and adult brain and skeletal muscle. Expression is specific to the telencephalon and ventral thalamus. There is an absence of expression in the cerebellum throughout development and also in adult.
Weight	58,160 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558797	CSB-PA059506	100ul	$297		Add to Cart

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