Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.Sharer J.D., J. Biol. Chem. 274:27553-27561(1999).The MGC Project Team; Genome Res. 14:2121-2127(2004).Van Valkenburgh H., J. Biol. Chem. 276:22826-22837(2001)
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human ARL2BP.
Involvement In Disease
Retinitis pigmentosa with or without situs inversus (RPSI)
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
Sharer J.D., J. Biol. Chem. 274:27553-27561(1999). The MGC Project Team; Genome Res. 14:2121-2127(2004). Van Valkenburgh H., J. Biol. Chem. 276:22826-22837(2001)
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ARL2BP protein
Subcellular Location
Cytoplasm, Mitochondrion intermembrane space, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Nucleus, Cytoplasm, cytoskeleton, spindle, Cytoplasm, cytoskeleton, cilium basal body
Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
Protein Families
ARL2BP family
Tissue Specificity
Expressed in retina pigment epithelial cells (at protein level). Widely expressed.
Weight
18 kDa
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.