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Home / Primary Antibodies / Recombinant Antibodies

Anti-TAGLN2 Antibody BHA11308273

SKU : BHA11308273

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Mfr.No.	BS8419
Alternative Names	Transgelin-2 ; Epididymis tissue protein Li 7e ; SM22-alpha homolog ; TAGLN2 ; KIAA0120 ; CDABP0035
Antigen	TAGLN2
Categories	Primary Antibodies
Chromosome Location	1q23.2
Clonality	polyclonal
Description	Transgelin (also designated SM22α), is expressed abundantly in smooth muscle cells. Transgelin-2 (also known as SM22α homolog) is a homolog of transgelin and is also expressed in smooth muscle cells and by peritoneal B-1 cells. The human transgelin-2 gene (designated TAGLN2), which is located on chromosome 1q231-q25, encodes a 199 amino acid protein that contains a calponin-like repeat and a calponin-homology (CH) domain. Transgelin-2 may function very similarly to transgelin. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is downregulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds actin, causing actin fibers to gel within minutes of binding. Binding of transgelin to actin occurs at a ratio of 1:6 actin monomers.
Host	Rabbit
Immunogen	Recombinant full length Human TAGLN2.
Reactivity	Human, Mouse
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P37802
Uniprot	P37802
Weight	22 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: TAGLN2 polyclonal antibody detects endogenous levels of TAGLN2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308273	BS8419	50µl	$234.89		Add to Cart
BHA11308273	BS8419	100µl	$368.22		Add to Cart

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