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Home / Primary Antibodies / IHC Antibodies

Anti-PCNA Antibody BHA11300453

SKU : BHA11300453

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Mfr.No.	BS1289
Alternative Names	Proliferating cell nuclear antigen ; Cyclin
Categories	Primary Antibodies
Chromosome Location	20p12.3
Clonality	polyclonal
Description	The proliferating cell nuclear antigen (PCNA), a protein synthesized in early G1 and S phases of the cell cycle, functions in cell cycle progression, DNA replication, and DNA repair. In early S phase, PCNA exhibits granular distribution and is absent from the nucleoli, however, in late S phase, it relocates to the nucleoli. PCNA exists in two basic forms, one involved in ongoing DNA replication. which localizes specifically to the nucleus, and a second, soluble form, not implicated in constant synthesis. Interestingly, the latter form degrades in the presence of organic solvents, rendering it undetectable by histological methods in tissues using organic fixatives, and thus also providing a method of visualizing only the synthesizing form.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 51-100 of Human PCNA.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P12004
Uniprot	P12004
Weight	29, 36 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: PCNA (I88) polyclonal antibody detects endogenous levels of PCNA protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300453	BS1289	50µl	$190.44		Add to Cart
BHA11300453	BS1289	100µl	$294.44		Add to Cart

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