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Home / Primary Antibodies / Recombinant Antibodies

Anti-NR0B1 Antibody BHA11304840

SKU : BHA11304840

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Mfr.No.	BS6516
Alternative Names	Nuclear receptor subfamily 0 group B member 1 ; DSS-AHC critical region on the X chromosome protein 1 ; Nuclear receptor DAX-1 ; NR0B1 ; AHC ; DAX1
Categories	Primary Antibodies
Chromosome Location	Xp21.2
Clonality	polyclonal
Description	AHC has been mapped to chromosome Xp21 at the same or close to an X-linked locus involved in sex determination, DSS (for dosage-sensitive sex reversal). The gene corresponding to DSS and AHC (designated DAX-1 for DSS-AHC critical region on the X chromosome, gene 1) has been cloned and shown to be deleted in AHC deletion patients and mutated in AHC non-deletion patients. The carboxy terminal 250 amino acids of the DAX-1-encoded protein, DAX-1, exhibits approximately 50% continuous similarity to the ligand-binding domain of the members of the nuclear hormone receptor superfamily while the amino terminal domain contains a putative DNA-binding motif. DAX-1 binds to retinoic acid responsive elements and down regulates retinoic acid receptor-mediated transcriptional activation.
Host	Rabbit
Immunogen	Recombinant full length Human NR0B1.
Reactivity	Human, Mouse
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P51843
Uniprot	P51843
Weight	53 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: NR0B1 polyclonal antibody detects endogenous levels of NR0B1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304840	BS6516	50µl	$234.89		Add to Cart
BHA11304840	BS6516	100µl	$368.22		Add to Cart

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