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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Eph receptor A1/EPHA1 Antibody Picoband®

SKU : BHA21006898

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Mfr.No.	PA1573, PA1573-10ug, PA1573-Biotin, PA1573-Cy3, PA1573-Dylight488, PA1573-Dylight550, PA1573-Dylight594, PA1573-FITC, PA1573-HRP, PA1573-APC, PA1573-PE, PA1573-iFluor647, PA1573-carrier-free
Alternative Names	Ephrin type-A receptor 1
Background	EPHA1, EPH receptor A1, is a protein that in humans is encoded by the EPHA1 gene. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The EPHA1 gene is mapped to 7q34-q35. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Eph receptor A1/EPHA1 Antibody catalog # PA1573. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent biional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human Eph receptor A1, identical to the related rat and mouse sequences.
Isotype	Rabbit IgG
Molecular Weight	113 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Ephrin type-A receptor 1;hEpha1;2.7.10.1;EPH tyrosine kinase;EPH tyrosine kinase 1;Erythropoietin-producing hepatoma receptor;Tyrosine-protein kinase receptor EPH;EPHA1;EPH, EPHT, EPHT1;
Tissue Specificity	Overexpressed in several carcinomas.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P21709
Gene Name	EPHA1
Sequence	Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
Subcellular Location	Cell membrane ; Single-pass type I membrane protein .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Rat, Mouse, By Heat<br>Weste blot, 0.1-0.5ug/ml, Human, Rat, Mouse<br>

Reference	1. Hattori, M., Osterfield, M., Flanagan, J. G.Regulated cleavage of a contact-mediated axon repellent.Science 289: 1360-1365, 2000.<br /><br />2. Torii, M., Hashimoto-Torii, K., Levitt, P., Rakic, P.Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling.Nature 461: 524-528, 2009. Note: Erratum: Nature 462: 674 only, 2009.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006898-1	PA1573	-	100 ug	$370		Add to Cart
BHA21006898-2	PA1573-10ug	Sample	10 ug	$99		Add to Cart
BHA21006898-3	PA1573-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006898-4	PA1573-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006898-5	PA1573-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006898-6	PA1573-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006898-7	PA1573-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006898-8	PA1573-FITC	FITC	100 ug	$570		Add to Cart
BHA21006898-9	PA1573-HRP	HRP	100 ug	$570		Add to Cart
BHA21006898-10	PA1573-APC	APC	100 ug	$670		Add to Cart
BHA21006898-11	PA1573-PE	PE	100 ug	$670		Add to Cart
BHA21006898-12	PA1573-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006898-13	PA1573-carrier-free	carrier-free	100 ug	$370		Add to Cart

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