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Home / Primary Antibodies / IHC Antibodies

Anti-CYP2D6 Antibody BHA11302915

SKU : BHA11302915

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Mfr.No.	BS5685
Alternative Names	Cytochrome P450 2D6 ; CYPIID6 ; Cytochrome P450-DB1 ; Debrisoquine 4-hydroxylase ; CYP2DL1
Antigen	CYP2D6
Categories	Primary Antibodies
Chromosome Location	22q13.2
Clonality	polyclonal
Description	Enhanced CYP2D6 activity has been related to malignancies of the bladder, liver, pharynx, and stomach and, especially, to cigarette-smoking-induced lung cancer. The data suggests that enhanced CYP2D6-mediated metabolism of one or more dietary and other environmental agents, to form a reactive intermediate, plays a role in cancer initiation and/or promotion in various tissues. CYP2D6 polymorphism, which is responsible for the variation in metabolism of debrisoquine 4-hydroxylase, is important in the metabolism of more than 30 drugs and environmental chemicals, including as much as 20% of all commonly prescribed drugs.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 430-475 of Human CYP2D6.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P10635
Uniprot	P10635
Weight	55 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: CYP2D6 (R450) polyclonal antibody detects endogenous levels of CYP2D6 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302915	BS5685	50µl	$190.44		Add to Cart
BHA11302915	BS5685	100µl	$294.44		Add to Cart

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