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Home / Primary Antibodies / IHC Antibodies

Anti-CYP2D6 Antibody BHA11302915

SKU : BHA11302915

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Mfr.No.	BS5685
Alternative Names	Cytochrome P450 2D6 ; CYPIID6 ; Cytochrome P450-DB1 ; Debrisoquine 4-hydroxylase ; CYP2DL1
Categories	Primary Antibodies
Chromosome Location	22q13.2
Clonality	polyclonal
Description	Enhanced CYP2D6 activity has been related to malignancies of the bladder, liver, pharynx, and stomach and, especially, to cigarette-smoking-induced lung cancer. The data suggests that enhanced CYP2D6-mediated metabolism of one or more dietary and other environmental agents, to form a reactive intermediate, plays a role in cancer initiation and/or promotion in various tissues. CYP2D6 polymorphism, which is responsible for the variation in metabolism of debrisoquine 4-hydroxylase, is important in the metabolism of more than 30 drugs and environmental chemicals, including as much as 20% of all commonly prescribed drugs.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 430-475 of Human CYP2D6.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P10635
Uniprot	P10635
Weight	55 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: CYP2D6 (R450) polyclonal antibody detects endogenous levels of CYP2D6 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302915	BS5685	50µl	$190.44		Add to Cart
BHA11302915	BS5685	100µl	$294.44		Add to Cart

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