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Home / Primary Antibodies / IHC Antibodies

Anti-CAPNS1 Antibody BHA11304826

SKU : BHA11304826

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Mfr.No.	BS6491
Alternative Names	Calpain small subunit 1 ; CSS1 ; Calcium-activated neutral proteinase small subunit ; CANP small subunit ; Calcium-dependent protease small subunit ; CDPS ; Calcium-dependent protease small subunit 1 ; Calpain regulatory subunit ; CAPNS1 ; CAPN4 ; CAPNS
Antigen	CAPNS1
Categories	Primary Antibodies
Chromosome Location	19q13.12
Clonality	polyclonal
Description	Calpain 1 is an intracellular calcium-dependent protease that cleaves cyto-skeletal and submembranous proteins. Calpains are nonlysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2+-dependent processes including cell fusion, mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit, designated Calpain reg, and one of three large catalytic subunits, designated Calpain 1, Calpain 2 and Calpain p94. Calpastatin regulates Calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpain 1 co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction.
Host	Rabbit
Immunogen	Recombinant full length Human CAPNS1.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P04632
Uniprot	P04632
Weight	28 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: CAPNS1 polyclonal antibody detects endogenous levels of CAPNS1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:2000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304826	BS6491	50µl	$234.89		Add to Cart
BHA11304826	BS6491	100µl	$368.22		Add to Cart

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