Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.Soreq H., Proc. Natl. Acad. Sci. U.S.A. 87:9688-9692(1990).Karpel R., Exp. Cell Res. 210:268-277(1994).Yang L., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
Host
Rabbit
Immunogen
Synthesized peptide derived from C-terminal of Human ACHE.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
Soreq H., Proc. Natl. Acad. Sci. U.S.A. 87:9688-9692(1990). Karpel R., Exp. Cell Res. 210:268-277(1994). Yang L., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ACHE protein.
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
Protein Families
Type-B carboxylesterase/lipase family
Tissue Specificity
Isoform H is highly expressed in erythrocytes.
Weight
58,352 Da
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.