Necessary for the synthesis of type III mucin. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans.Nakayama J., Proc. Natl. Acad. Sci. U.S.A. 96:8991-8996(1999).The MGC Project Team; Genome Res. 14:2121-2127(2004).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human A4GNT.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Necessary for the synthesis of type III mucin. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans.
Nakayama J., Proc. Natl. Acad. Sci. U.S.A. 96:8991-8996(1999). The MGC Project Team; Genome Res. 14:2121-2127(2004).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total A4GNT protein.
Subcellular Location
Golgi apparatus membrane, Single-pass type II membrane protein