Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.
Clonality
polyclonal
Host
Rabbit
Immunogen
mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Immunogen Region
mitogen-actIVated protein kinase kinase kinase 7 interacting protein 2