Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.
Clonality
polyclonal
Host
Rabbit
Immunogen
mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Immunogen Region
mitogen-actIVated protein kinase kinase kinase 7 interacting protein 2
Isotype
IgG
Molecular Weight
77 kDa
Reactivity
Human, Rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500
Synonyms
KIAA0733, MAP3K7IP2
Uniprot
Q9NYJ8
Gene Id
23118
Research Area
Immunology
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000; IHC: 1:50-1:500
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09979.pdf" target="_blank">Data Sheet</ a>