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Home / Primary Antibodies / Polyclonal Antibodies

PRPF8 antibody

SKU : BHA10806813

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Mfr.No.	FNab06821
Alternative Names	PRPC8
Background	Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.
Host	Rabbit
Immunogen	PRP8 pre-mRNA processing factor 8 homolog
Isotype	IgG
Molecular Weight	274 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	PRPC8

Uniprot	Q6P2Q9
Gene Id	10594
Research Area	Epigenetics, Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP
Description	ELISA ; WB ; IP
Tested Application	WB: 1:500 - 1:1000; IHC: 1:50 - 1:100

Manual	FNab06821.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806813	FNab06821	100ug	$240		Add to Cart

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