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Home / Antibodies

PDCD1 Antibody / PD-1 / PD1 (V8347)

SKU : BHA17117938

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NSJ Bioreagents

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Mfr.No.	V8347, V8347-20UG, V8347-100UG
Antigen	PDCD1
Clonality	Monoclonal
Description	PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally, Pdcd1 mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. <strong>The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells).</strong>
Formulation	0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Rat
Immunogen Region	PDCD1 transfected BHK cells were used as the immunogen for the PD1 antibody.
Isotype	IgG2a,kappa
Predicted Reactivity	Mouse
Reactivity	Mouse
Recombinant	No

Uniprot	Q02242
Clone No	RMP1-14

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the PD1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	Neutralization, ELISA, FACS, IF
Dilution	ELISA (order BSA/azide-free format for coating),Neutralization Studies (order BSA/azide-free format),Flow cytometry: 1-2ug/million cells in 0.1ml,Immunofluorescence: 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17117938-1	V8347-20UG	20ug	$219		Add to Cart
BHA17117938-2	V8347-100UG	100ug	$499		Add to Cart

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