Optimal dilutions/concentrations should be determined by the end user.
Uniprotkb
Q04206 (UniProt, ExPASy)
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Note
This product is for research use only.
Gene Symbol
RELA
Tested Application
IHC
Buffer
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Gene Id
5970
Target
NF-kB p65 (pS281)
Purification
Purified by affinity chromatography.
Description
Phospho-NF-kB p65 (Ser281) Antibody detects endogenous levels of NF-kB p65 only when phosphorylated at Serine 281. NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm.