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Home / Primary Antibodies / IHC Antibodies

Phospho-STAT5A (Ser780) Antibody

SKU : BHA10560315

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA137661
Alternative Names	MGF; MPF; Mammary gland factor; STA5A,; STAT5
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369.Dentelli P, et al. (1999) J Immunol. 163: 2151-2159.Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of serine 780 (R-L-S(p)-P-P) derived from Human STAT5A.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription. Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369. Dentelli P, et al. (1999) J Immunol. 163: 2151-2159. Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of STAT5A only when phosphorylated at serine 780.
Subcellular Location	Cytoplasm, Nucleus

Uniprot	P42229
Database Links	HGNC:11366 OMIM:601511 KEGG:hsa:6776 STRING:9606.ENSP00000341208 UniGene:Hs.437058
Function	Carries out a dual function
Pathway	ErbB signaling pathway Jak-STAT signaling pathway Necroptosis Th1 and Th2 cell differentiation Th17 cell differentiation AGE-RAGE signaling pathway in diabetic complications
Protein Families	Transcription factor STAT family

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:100

Tested Application

ELISA,WB,IHC;WB:1:500-1:1000,IHC:1:50-1:100

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560315	CSB-PA137661	100ul	$360		Add to Cart

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