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Home / Primary Antibodies / IHC Antibodies

HNRNPC Antibody

SKU : BHA10559806

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA966696
Alternative Names	HNRNPC; HNRPC; Heterogeneous nuclear ribonucleoproteins C1/C2; ROC; hnRNP C1 / hnRNP C2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.Burd C.G., Proc. Natl. Acad. Sci. U.S.A. 86:9788-9792(1989).Swanson M.S., Mol. Cell. Biol. 7:1731-1739(1987).Merrill B.M., Nucleic Acids Res. 17:8441-8449(1989).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human hnRNP C1/C2.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Burd C.G., Proc. Natl. Acad. Sci. U.S.A. 86:9788-9792(1989). Swanson M.S., Mol. Cell. Biol. 7:1731-1739(1987). Merrill B.M., Nucleic Acids Res. 17:8441-8449(1989).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total hnRNP C1/C2 protein.
Subcellular Location	Nucleus

Uniprot	P07910
Database Links	HGNC:5035 OMIM:164020 KEGG:hsa:3183 STRING:9606.ENSP00000319690 UniGene:Hs.508848
Function	Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles
Protein Families	RRM HNRPC family, RALY subfamily

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF, WB ; ELISA ; IHC ; IF

Dilution

WB	1:500-1:3000
IHC	1:50-1:100
IF	1:100-1:500

Tested Application

ELISA,WB,IHC,IF;WB:1:500-1:3000,IHC:1:50-1:100,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559806	CSB-PA966696	100ul	$297		Add to Cart

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