Homeodomain-interacting protein kinase 4; EC 2.7.11.1; HIPK4;
Antigen
HIPK4
Categories
Primary Antibodies
Clonality
polyclonal
Description
Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter By similarity. May act as a corepressor of transcription factors Potential.Ota T., Nat. Genet. 36:40-45(2004).The MGC Project Team, Genome Res. 14:2121-2127(2004).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human HIPK4.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter By similarity. May act as a corepressor of transcription factors Potential.
Ota T., Nat. Genet. 36:40-45(2004). The MGC Project Team, Genome Res. 14:2121-2127(2004).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total HIPK4 protein.
Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity). May act as a corepressor of transcription factors (Potential).
Pathway
Cellular senescence
Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.