HSPF1; DNAJ E. COLI HOMOLOG OF SUBFAMILY B MEMBER 1; HEAT-SHOCK 40-KD PROTEIN 1;
Antigen
DNAJB1
Categories
Primary Antibodies
Clonality
polyclonal
Description
Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP.M. Patricia Hern篓顣攄ez, J. Biol. Chem., Mar 2002; 277: 11873 - 11881.Annemieke A. Michels, J. Biol. Chem., Dec 1997; 272: 33283.Fritha Hennessy, Protein Sci., Jul 2005; 14: 1697 - 1709.Mark W. Melville, PNAS, Jan 1997; 94: 97.
Host
Rabbit
Immunogen
Synthesized peptide derived from Human HSP40.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP.
M. Patricia Hern?ez, J. Biol. Chem., Mar 2002; 277: 11873 - 11881. Annemieke A. Michels, J. Biol. Chem., Dec 1997; 272: 33283. Fritha Hennessy, Protein Sci., Jul 2005; 14: 1697 - 1709. Mark W. Melville, PNAS, Jan 1997; 94: 97.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total HSP40 protein.
Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response
Pathway
Protein processing in endoplasmic reticulum
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.