Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471(1995).Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787(1999).Boyd J.M., EMBO J. 12:469-478(1993).
Host
Rabbit
Immunogen
Synthesized non-phosphopeptide derived from Human CtBP1 around the phosphorylation site of serine 422 (A-P-S(p)-P-G).
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471(1995). Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787(1999). Boyd J.M., EMBO J. 12:469-478(1993).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total CtBP1 protein.
Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Pathway
Notch signaling pathway Wnt signaling pathway
Protein Families
D-isomer specific 2-hydroxyacid dehydrogenase family
Tissue Specificity
Expressed in germinal center B-cells.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.