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Home / Primary Antibodies / IHC Antibodies

Anti-C5AR1 Antibody BHA11300679

SKU : BHA11300679

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Mfr.No.	BS1522
Alternative Names	C5a anaphylatoxin chemotactic receptor 1 ; C5a anaphylatoxin chemotactic receptor ; C5a-R ; C5aR ; CD88 ; C5AR1 ; C5AR ; C5R1
Categories	Primary Antibodies
Chromosome Location	19q13.32
Clonality	polyclonal
Description	C5a receptor (C5aR), also known as CD88, is a G protein-coupled integral membrane protein. CD88, which is expressed on neutrophils, monocytes, macrophages, hepatocytes and mast cells, as well as on various epithelial and endothelial cells, serves as a receptor for the inflammatory peptide C5a. Research studies suggest a role for CD88 in the inflammatory response. The binding of C5a to CD88 has been shown to elicit increased production of acute phase proteins in liver. In brain, an increased production of CD88 has been shown to be associated with inflammation. Research also indicates a role for C5a/C5aR in the pathogenesis of rheumatoid arthritis, as well as a heightened responsiveness of human bronchial epithelial cells (HBECs) to C5a upon exposure of these cells to cigarette smoke and other environmental irritants.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 300-350 of Human C5aR.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P21730
Uniprot	P21730
Weight	45 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: CD88/C5aR (S334) polyclonal antibody detects endogenous levels of D88/C5aR protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC, IF

Description

IHC ; IF

Dilution

IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300679	BS1522	50µl	$190.44		Add to Cart
BHA11300679	BS1522	100µl	$294.44		Add to Cart

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