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Home / Primary Antibodies / IHC Antibodies

Anti-CLDN5 Antibody BHA11300251

SKU : BHA11300251

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Mfr.No.	BS1069
Alternative Names	Claudin5 ; Claudin 5 ; Transmembrane protein deleted in VCFS ; TMDVCF ; CLDN5 ; AWAL ; TMVCF
Categories	Primary Antibodies
Chromosome Location	22q11.21
Clonality	polyclonal
Description	The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-5 is expressed in the endothelial junctions of the rat liver and in junctions of acinar cells of the pancreas. Human claudin-5 is abundantly expressed in adult lung, heart and skeletal muscle and is deleted in patients with velocardiofacial syndrone, which is characterized by cleft palate, facial dysmorphology and conotruncal heart defects.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 171-220 of Human Claudin-5.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O00501
Uniprot	O00501
Weight	23 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Claudin 5 (S201) polyclonal antibody detects endogenous levels of Claudin 5 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300251	BS1069	50µl	$190.44		Add to Cart
BHA11300251	BS1069	100µl	$294.44		Add to Cart

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