Anti-ACTG1/POTEKP/ACTB Antibody BHA11300190

Mfr.No.	BS1002
Alternative Names	ACTB ; Beta-actin ; Actin ; cytoplasmic 1 ; β-actin ; β actin ; βactin ; actin-β ; actin β, POTEKP, Kappa-actin, ACTBL3, Gamma-actin, ACTG1, ACTG
Categories	Primary Antibodies
Clonality	polyclonal
Description	All eukaryotic cells express Actin, which often constitutes as much as 50% of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one Actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of Actin are present in mammalian tissues and fall into three classes. Alpha Actin expression is limited to various types of muscle, whereas beta and gamma are the principle constituents of filaments in other tissues. Members of the small GTPase family regulate the organization of the Actin cytoskeleton. Rho controls the assembly of Actin stress fibers and focal adhesion, Rac regulates Actin filament accumulation at the plasma membrane and Cdc42 stimulates formation of filopodia.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids C-terminus of Human Actin.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: Actin (E361) polyclonal antibody detects endogenous levels of Actin protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.