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ELISA Kit for Rat Nitric oxide synthase, inducible

SKU : BHE13808315

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0837r
Alternative Names	Inducible NO synthase ; Inducible NOS ; NOS type II ; Peptidyl-cysteine S-nitrosylase NOS2
Categories	Elisa
Function	Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
Specificity	Natural and recombinant Rat Nitric oxide synthase, inducible
Detection Range	1.56-100nmol/L
Entryname	NOS2_RAT
Method Type	Sandwich
Platform	PF00667
Protein Name	Nitric oxide synthase, inducible
Sensitivity	0.78nmol/L
Sequence	50: MACPWKFLFR ; VKSYQGDLKE ; EKDINNNVEK ; TPGAIPSPTT ; QDDPKSHKHQ ; 100: NGFPQFLTGT ; AQNVPESLDK ; LHVTPSTRPQ ; HVRIKNWGNG ; EIFHDTLHHK ; 150: ATSDISCKSK ; LCMGSIMNSK ; SLTRGPRDKP ; TPVEELLPQA ; IEFINQYYGS ; 200: FKEAKIEEHL ; ARLEAVTKEI ; ETTGTYQLTL ; DELIFATKMA ; WRNAPRCIGR ; 250: IQWSNLQVFD ; ARSCSTASEM ; FQHICRHILY ; ATNSGNIRSA ; ITVFPQRSDG ; 300: KHDFRIWNSQ ; LIRYAGYQMP ; DGTIRGDPAT ; LEFTQLCIDL ; GWKPRYGRFD ; 350: VLPLVLQAHG ; QDPEVFEIPP ; DLVLEVTMEH ; PKYEWFQELG ; LKWYALPAVA ; 400: NMLLEVGGLE ; FPACPFNGWY ; MGTEIGVRDF ; CDTQRYNILE ; EVGRRMGLET ; 450: HTLASLWKDR ; AVTEINAAVL ; HSFQKQNVTI ; MDHHTASESF ; MKHMQNEYRA ; 500: RGGCPADWIW ; LVPPVSGSIT ; PVFHQEMLNY ; VLSPFYYYQI ; EPWKTHIWQD ; 550: EKLRPRRREI ; RFTVLVKAVF ; FASVLMRKVM ; ASRVRATVLF ; ATETGKSEAL ; 600: ARDLAALFSY ; AFNTKVVCME ; QYKANTLEEE ; QLLLVVTSTF ; GNGDCPSNGQ ; 650: TLKKSLFMMK ; ELGHTFRYAV ; FGLGSSMYPQ ; FCAFAHDIDQ ; KLSHLGASQL ; 700: APTGEGDELS ; GQEDAFRSWA ; VQTFRAACET ; FDVRSKHCIQ ; IPKRYTSNAT ; 750: WEPEQYKLTQ ; SPESLDLNKA ; LSSIHAKNVF ; TMRLKSLQNL ; QSEKSSRTTL ; 800: LVQLTFEGSR ; GPSYLPGEHL ; GIFPGNQTAL ; VQGILERVVD ; CSSPDQTVCL ; 850: EVLDESGSYW ; VKDKRLPPCS ; LRQALTYFLD ; ITTPPTQLQL ; HKLARFATEE ; 900: THRQRLEALC ; QPSEYNDWKF ; SNNPTFLEVL ; EEFPSLRVPA ; AFLLSQLPIL ; 950: KPRYYSISSS ; QDHTPSEVHL ; TVAVVTYRTR ; DGQGPLHHGV ; CSTWINNLKP ; 1000: EDPVPCFVRS ; VSGFQLPEDP ; SQPCILIGPG ; TGIAPFRSFW ; QQRLHDSQHR ; 1050: GLKGGRMTLV ; FGCRHPEEDH ; LYQEEMQEMV ; RKGVLFQVHT ; GYSRLPGKPK ; 1100: VYVQDILQKE ; LADEVFSVLH ; GEQGHLYVCG ; DVRMARDVAT ; TLKKLVAAKL ; 1147: NLSEEQVEDY ; FFQLKSQKRY ; HEDIFGAVFS ; YGAKKGNTLE ; EPKGTRL
Sequence Length	1147
String	Q06518
Sub Unit	Homodimer. Binds SLC9A3R1.

Uniprot	Q06518
Gene Name	Nos2
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:24599
Unigene	Rn.10400

Reference	1. "Cloning of inducible nitric oxide synthase in rat vascular smooth muscle cells." Nunokawa Y., Ishida N., Tanaka S. Biochem. Biophys. Res. Commun.191:89-94(1993) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Vascular smooth muscle. 2. "Cloning and expression of cytokine-inducible nitric oxide synthase cDNA from rat islets of Langerhans." Karlsen A.E., Andersen H.U., Vissing H., Larsen P.M., Fey S.J., Cuartero B.G., Madsen O.D., Petersen J.S., Mortensen S.B., Mandrup-Poulsen T., Boel E., Nerup J. Diabetes44:753-758(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Wistar. tissue: Pancreatic islet. 3. "Cloning and expression of inducible nitric oxide synthase from rat astrocytes." Galea E., Reis D.J., Feinstein D.L. J. Neurosci. Res.37:406-414(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Sprague-Dawley. tissue: Astrocyte. 4. "Molecular cloning of a cDNA encoding an inducible calmodulin-dependent nitric-oxide synthase from rat liver and its expression in COS 1 cells." Adachi H., Iida S., Oguchi S., Ohshima H., Suzuki H., Nagasaki K., Kawasaki H., Sugimura T., Esumi H. Eur. J. Biochem.217:37-43(1993) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE tissue: Liver. 5. "Hepatocytes and macrophages express an identical cytokine inducible nitric oxide synthase gene." Wood E.R., Berger H. Jr., Sherman P.A., Lapetina E.G. Biochem. Biophys. Res. Commun.191:767-774(1993) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Sprague-Dawley. tissue: Hepatocyte. 6. "cDNA cloning and expression of inducible nitric oxide synthase from rat vascular smooth muscle cells." Geng Y.J., Almquist M., Hansson G.K. Biochim. Biophys. Acta1218:421-424(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Sprague-Dawley. tissue: Aorta. 7. "Cloning of an inducible nitric oxide synthase from rat polymorphonuclear neutrophils." Kosuga K., Yui Y., Hattori R., Sase K., Eizawa H., Aoyama T., Inoue R., Sasayama S. Endothelium2:217-221(1994) [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 8. "Sequence analysis of inducible nitric oxide synthase in rat kidney, lung, and uterus." Tsutsumishita Y., Kawai Y., Takahara H., Onda T., Miyoshi J., Futaki S., Niwa M. Biol. Pharm. Bull.19:1374-1376(1996) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 9. "Complete coding sequence of inducible nitric oxide synthase from human heart and skeletal muscle of patients with chronic heart failure." Adams V., Krabbes S., Jiang H., Yu J., Rahmel A., Gielen S., Schuler G., Hambrecht R. Nitric Oxide2:242-249(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 10. "Vascular smooth muscle nitric oxide synthase anomalies in Dahl/Rapp salt-sensitive rats." Chen P.Y., Gladish R.D., Sanders P.W. Hypertension31:918-924(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 426-788 strain: Dahl/Rapp salt sensitive strain. tissue: Vascular smooth muscle. 11. "Advances in the studies of NO synthesis regulation in mesanglial cells." Saura M., Zaragoza C., Martinez-Dalmau R., Perez-Sala D., Lamas S. Nefrologia16:35-39(1996) [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 509-740 strain: Wistar. tissue: Renal glomerulus. 12. "Location of an inducible nitric oxide synthase mRNA in the normal kidney." Morrissey J.J., McCracken R., Kaneto H., Vehaskari M., Montani D., Klahr S. Kidney Int.45:998-1005(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 479-655 strain: Sprague-Dawley. tissue: Renal glomerulus. 13. "Isolation and characterization of iNOS from rat cardiocytes." Michel T., Balligand J.-L. Submitted (1994-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 420-479 tissue: Myocardium.

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