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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse TNF receptor-associated factor 4

SKU : BHE13810673

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15310m
Alternative Names	Cysteine-rich motif associated to RING and Traf domains protein 1 ; Cart1
Categories	Elisa
Function	Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions (By similarity). Required for normal skeleton development, and for normal development of the respiratory tract.
Specificity	Natural and recombinant Mouse TNF receptor-associated factor 4
Subcellular Location	Cytoplasm Nucleus Cytoplasm perinuclear region Cell junction tight junction Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasm cytoskeleton
Entryname	TRAF4_MOUSE
Platform	PF00917
Protein Name	TNF receptor-associated factor 4
Sequence	50: MPGFDYKFLE ; KPKRRLLCPL ; CGKPMREPVQ ; VSTCGHRFCD ; TCLQEFLSEG ; 100: VFKCPEDQLP ; LDYAKIYPDP ; ELEVQVLGLA ; IRCIHSEEGC ; RWSGPLRHLQ ; 150: GHLNTCSFNV ; VPCPNRCPAK ; LSRRDLPAHL ; QHDCPKRRLK ; CEFCGCDFSG ; 200: EAYESHEGVC ; PQESVYCENK ; CGARMMRRLL ; AQHATSECPK ; RTQPCAYCTK ; 250: EFVYDTIQSH ; QYQCPRLPVP ; CPNQCGVGTV ; AREDLPTHLK ; DSCSTAFVLC ; 300: PFKESGCKHR ; CPKLAMGRHV ; EESVKPHLAM ; MCALVSRQRQ ; ELQELRRELE ; 350: ELSIGSDGVL ; IWKIGSYGRR ; LQEAKAKPNL ; ECFSPAFYTH ; KYGYKLQVSA ; 400: FLNGNGSGEG ; THLSIYIRVL ; PGAFDNLLEW ; PFARRVTFSL ; LDQSDPGLAK ; 450: PQHVTETFHP ; DPNWKNFQKP ; GTWRGSLDES ; SLGFGYPKFI ; SHQDIRKRNY ; 470: VRDDAVFIRA ; SVELPRKILS ;
Sequence Length	470
String	Q61382
Sub Unit	Homotrimer (Probable). Interacts with LTBR/TNFRSF3, NGFR/TNFRSF16, RPS6KB1 and TGFB1I1. Interacts with SMURF1. Interacts (via TRAF domain) with MAP3K4 (via kinase domain). Interacts with NCF1, TICAM1, IRAK1 and TRAF6, and is probably part of a complex containing TRAF4, NCF1, TICAM1, IRAK1 and TRAF6.

Uniprot	Q61382
Gene Name	Traf4
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:22032
Unigene	Mm.390418

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810673	E15310m	96T	$776		Add to Cart

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