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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Glutamate receptor 2

SKU : BHE13805471

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11294h
Alternative Names	AMPA-selective glutamate receptor 2 ; GluR-B ; GluR-K2 ; Glutamate receptor ionotropic ; AMPA 2 ; GluA2 ; GLUR2
Categories	Elisa
Function	Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Specificity	Natural and recombinant Human Glutamate receptor 2
Subcellular Location	Cell membrane Multi-pass membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression.
Detection Range	0.312-20ng/mL
Entryname	GRIA2_HUMAN
Method Type	Sandwich
Platform	PF01094
Protein Name	Glutamate receptor 2
Sensitivity	0.143ng/mL
Sequence	50: MQKIMHISVL ; LSPVLWGLIF ; GVSSNSIQIG ; GLFPRGADQE ; YSAFRVGMVQ ; 100: FSTSEFRLTP ; HIDNLEVANS ; FAVTNAFCSQ ; FSRGVYAIFG ; FYDKKSVNTI ; 150: TSFCGTLHVS ; FITPSFPTDG ; THPFVIQMRP ; DLKGALLSLI ; EYYQWDKFAY ; 200: LYDSDRGLST ; LQAVLDSAAE ; KKWQVTAINV ; GNINNDKKDE ; MYRSLFQDLE ; 250: LKKERRVILD ; CERDKVNDIV ; DQVITIGKHV ; KGYHYIIANL ; GFTDGDLLKI ; 300: QFGGANVSGF ; QIVDYDDSLV ; SKFIERWSTL ; EEKEYPGAHT ; TTIKYTSALT ; 350: YDAVQVMTEA ; FRNLRKQRIE ; ISRRGNAGDC ; LANPAVPWGQ ; GVEIERALKQ ; 400: VQVEGLSGNI ; KFDQNGKRIN ; YTINIMELKT ; NGPRKIGYWS ; EVDKMVVTLT ; 450: ELPSGNDTSG ; LENKTVVVTT ; ILESPYVMMK ; KNHEMLEGNE ; RYEGYCVDLA ; 500: AEIAKHCGFK ; YKLTIVGDGK ; YGARDADTKI ; WNGMVGELVY ; GKADIAIAPL ; 550: TITLVREEVI ; DFSKPFMSLG ; ISIMIKKPQK ; SKPGVFSFLD ; PLAYEIWMCI ; 600: VFAYIGVSVV ; LFLVSRFSPY ; EWHTEEFEDG ; RETQSSESTN ; EFGIFNSLWF ; 650: SLGAFMQQGC ; DISPRSLSGR ; IVGGVWWFFT ; LIIISSYTAN ; LAAFLTVERM ; 700: VSPIESAEDL ; SKQTEIAYGT ; LDSGSTKEFF ; RRSKIAVFDK ; MWTYMRSAEP ; 750: SVFVRTTAEG ; VARVRKSKGK ; YAYLLESTMN ; EYIEQRKPCD ; TMKVGGNLDS ; 800: KGYGIATPKG ; SSLRNAVNLA ; VLKLNEQGLL ; DKLKNKWWYD ; KGECGSGGGD ; 850: SKEKTSALSL ; SNVAGVFYIL ; VGGLGLAMLV ; ALIEFCYKSR ; AEAKRMKVAK ; 883: NAQNINPSSS ; QNSQNFATYK ; EGYNVYGIES ; VKI
Sequence Length	883
String	P42262
Sub Unit	Homotetramer or heterotetramer of pore-forming glutamate receptor subunits. Tetramers may be formed by the dimerization of dimers. May interact with MPP4. Forms a ternary complex with GRIP1 and CSPG4. Interacts with PICK1 (via PDZ domain). Interacts with PRKCABP, GRIP1 and GRIP2 (By similarity). Interacts with GRIA1 and SYNDIG1 (By similarity). Interacts with LRFN1 (By similarity). Found in a complex with GRIA1, GRIA3, GRIA4, CNIH2, CNIH3, CACNG2, CACNG3, CACNG4, CACNG5, CACNG7 and CACNG8. Interacts with CACNG5.

Uniprot	P42262
Gene Name	GRIA2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:2891
Unigene	Hs.32763

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805471	E11294h	96T	$736		Add to Cart

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