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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Enhancer of filamentation 1

SKU : BHE13801982

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15036h
Alternative Names	CRK-associated substrate-related protein ; CAS-L ; Cas scaffolding protein family member 2 ; Neural precursor cell expressed developmentally down-regulated protein 9 ; NEDD-9 ; Renal carcinoma antigen NY-REN-12 ; p105 ; CASL ; CASS2
Categories	Elisa
Function	Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form.
Specificity	Natural and recombinant Human Enhancer of filamentation 1
Subcellular Location	Enhancer of filamentation 1 p55 Cytoplasm cytoskeleton spindle
Detection Range	0.156-10ng/mL
Entryname	CASL_HUMAN
Method Type	Sandwich
Platform	PF12026
Protein Name	Enhancer of filamentation 1
Sensitivity	0.078ng/ml
Sequence	50: MKYKNLMARA ; LYDNVPECAE ; ELAFRKGDIL ; TVIEQNTGGL ; EGWWLCSLHG ; 100: RQGIVPGNRV ; KLLIGPMQET ; ASSHEQPASG ; LMQQTFGQQK ; LYQVPNPQAA ; 150: PRDTIYQVPP ; SYQNQGIYQV ; PTGHGTQEQE ; VYQVPPSVQR ; SIGGTSGPHV ; 200: GKKVITPVRT ; GHGYVYEYPS ; RYQKDVYDIP ; PSHTTQGVYD ; IPPSSAKGPV ; 250: FSVPVGEIKP ; QGVYDIPPTK ; GVYAIPPSAC ; RDEAGLREKD ; YDFPPPMRQA ; 300: GRPDLRPEGV ; YDIPPTCTKP ; AGKDLHVKYN ; CDIPGAAEPV ; ARRHQSLSPN ; 350: HPPPQLGQSV ; GSQNDAYDVP ; RGVQFLEPPA ; ETSEKANPQE ; RDGVYDVPLH ; 400: NPPDAKGSRD ; LVDGINRLSF ; SSTGSTRSNM ; STSSTSSKES ; SLSASPAQDK ; 450: RLFLDPDTAI ; ERLQRLQQAL ; EMGVSSLMAL ; VTTDWRCYGY ; MERHINEIRT ; 500: AVDKVELFLK ; EYLHFVKGAV ; ANAACLPELI ; LHNKMKRELQ ; RVEDSHQILS ; 550: QTSHDLNECS ; WSLNILAINK ; PQNKCDDLDR ; FVMVAKTVPD ; DAKQLTTTIN ; 600: TNAEALFRPG ; PGSLHLKNGP ; ESIMNSTEYP ; HGGSQGQLLH ; PGDHKAQAHN ; 650: KALPPGLSKE ; QAPDCSSSDG ; SERSWMDDYD ; YVHLQGKEEF ; ERQQKELLEK ; 700: ENIMKQNKMQ ; LEHHQLSQFQ ; LLEQEITKPV ; ENDISKWKPS ; QSLPTTNSGV ; 750: SAQDRQLLCF ; YYDQCETHFI ; SLLNAIDALF ; SCVSSAQPPR ; IFVAHSKFVI ; 800: LSAHKLVFIG ; DTLTRQVTAQ ; DIRNKVMNSS ; NQLCEQLKTI ; VMATKMAALH ; 834: YPSTTALQEM ; VHQVTDLSRN ; AQLFKRSLLE ; MATF
Sequence Length	834
String	Q14511
Sub Unit	Interacts with BCAR3 and SH2D3C (By similarity). Homodimer. Can heterodimerize with HLH proteins ID2, E12, E47 and also with p130cas. Forms complexes in vivo with related adhesion focal tyrosine kinase (RAFTK), adapter protein CRKL and LYN kinase. Interacts with MICAL and TXNL4/DIM1.

Uniprot	Q14511
Gene Name	NEDD9
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:4739
Unigene	Hs.37982

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801982	E15036h	96T	$736		Add to Cart

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