ELISA Kit for Bovine Eukaryotic translation initiation factor 4E-binding protein 1

Mfr.No.	E2693b
Categories	Elisa
Function	Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Specificity	Natural and recombinant Bovine Eukaryotic translation initiation factor 4E-binding protein 1
Entryname	4EBP1_BOVIN
Platform	PF05456
Protein Name	Eukaryotic translation initiation factor 4E-binding protein 1
Sequence	50: MSGGSSCSQT ; PSRAIPTTRR ; VVLADGVQLP ; PGDYSTTPGG ; TLFSTTPGGT ; 100: RIIYDRKFLM ; ECRNSPVTKT ; PPRDLPTIPG ; VTSPTGDEPP ; TEARQNHLRS ; 118: SPEDKPAGGE ; ESQFEMDI
Sequence Length	118
String	Q0P5A7
Sub Unit	Nonphosphorylated EIF4EBP1 competes with EIF4G1/EIF4G3 to interact with EIF4E; insulin stimulated MAP-kinase (MAPK1 and MAPK3) or mTORC1 phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. Interacts with RPTOR.

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-08) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Fetal spinal cord.

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHE13800251	E2693b	96T	$900		Add to Cart