Human Interferon Alpha/Beta Receptor 2

Mfr.No.

E5493Hu

Sensitivity

0.026ng/ml

Detection Range

0.05-10ng/ml

Reactivity

Human

Assay Duration

1h 30m

Assay Type

Sandwich

Alternative Names

IFN-alpha binding protein;IFN-alpha/beta receptor 2;IFNAR 2;IFNAR2;IFN-R-2;Interferon alpha binding protein;Interferon alpha/beta receptor 2;Type I interferon receptor 2

Molecular Weight

57759

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Precision

We measured random samples of E5493Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	2.1	0.1	4.9
Intra-Assay	2	18	4.6	0.2	4.3
Intra-Assay	3	18	1.6	0.11	7.1

Background

Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation (PubMed: 26424569, PubMed: 32972995). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1 (PubMed: 8181059, PubMed: 7665574, PubMed: 7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity (PubMed: 7759950).

Protocol

These standard curves of E5493Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
12ng/ml	2.089	2.063	2.003
	2.037
6ng/ml	1.614	1.682	1.621
	1.749
3ng/ml	1.195	1.148	1.087
	1.1
1.5ng/ml	0.712	0.675	0.615
	0.639
0.75ng/ml	0.475	0.454	0.394
	0.433
0ng/ml	0.063	0.06	0
	0.057

Gene ID	3455
UniProt ID	P48551

Research Area	Immunology

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12106855	E5493Hu	48T	$320		Add to Cart
BHE12106855	E5493Hu	96T	$458		Add to Cart

Human Interferon Alpha/Beta Receptor 2 - IFNAR2 ELISA Kit

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