BHE12106795
Transcription factor required for the development of the heart and the spleen (PubMed: 22560297). During heart development, acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). Binds to the core DNA motif of NPPA promoter (PubMed: 22849347, PubMed: 26926761). Together with PBX1, required for spleen development through a mechanism that involves CDKN2B repression (PubMed: 22560297).
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