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Human Heterogeneous Nuclear Ribonucleoprotein L - HNRNPL ELISA

BHE12104575

Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements (PubMed: 11809897, PubMed: 22570490, PubMed: 24164894, PubMed: 25623890, PubMed: 26051023). Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts (PubMed: 2687284). Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter (PubMed: 11809897).

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