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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hPD-1/hIL1B
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Tumor Research
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hSEMA4D
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hPD-L1/hOX40
- Strain : Embryo cryopres
- KI/KO Gene : Tnfrsf4
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Tnf
- Description : hPD-1(NM-HU-000
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hPD-1/hVEGFR2
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hTIM3
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
-
hPD-L1/hCTLA-4
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Ctl
- Description : hPD-L1(NM-HU-00
-
hPD-L1/hCD73(2)
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Cd2
- Description : hPD-L1(NM-HU-00
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hPD-L1/hCD28
- Strain : Repository Live
- KI/KO Gene : Cd274
- Research Application : Tumor Research
- Nomenclature : C57BL/6Smoc-Cd2
- Description : hPD-L1(NM-HU-00
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hPD-L2(BALB/c)
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1lg2
- Research Application : Immunotherapy
- Nomenclature : BALB/cAnSmoc-Pd
- Description : The endogenous
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hPD-L1/hSIRPA(2)
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Sir
- Description : hPD-L1(NM-HU-00
-
hSIGLEC15(BALB/c)
- Strain : Repository Live
- KI/KO Gene : SIGLEC15
- Research Application : Immunotherapy
- Nomenclature : BALB/cAnSmoc-Si
- Description : The endogenous
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hSIRPA(BALB/c,2)
- Strain : Embryo cryopres
- KI/KO Gene : IL11
- Research Application : Immunotherapy
- Nomenclature : BALB/cAnSmoc-Si
- Description : The endogenous
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hSIRPA(2)/hCD47/hPD-1/hPD-L1
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Sir
- Description : hSIRPA(2)(NM-HU
-
hSIGLEC8(2)
- Strain : Embryo cryopres
- KI/KO Gene : Siglecf
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Sig
- Description : The endogenous
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hTIGIT(BALB/c,2)
- Strain : Repository Live
- KI/KO Gene : Tigit
- Research Application : Humanized Drug
- Nomenclature : BALB/cAnSmoc-Ti
- Description : The endogenous
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