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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hIL4/hIL4R(BALB/c)
- Strain : Repository Live
- KI/KO Gene : IL4
- Research Application : Humanized Drug
- Nomenclature : BALB/cAnSmoc-Il
- Description : The endogenous
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hIL9(BALB/c)
- Strain : Repository Live
- KI/KO Gene : Il9
- Research Application : Humanized Drug
- Nomenclature : BALB/cAnSmoc-Il
- Description : The endogenous
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hLAIR1/hPD-1/hPD-L1
- Strain : Embryo cryopres
- KI/KO Gene : LAIR1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Lai
- Description : hLAIR1(NM-HU-20
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hPD-1/hICOS(2)
- Strain : Embryo cryopres
- KI/KO Gene : ICOS
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hCD3E
- Strain : Embryo cryopres
- KI/KO Gene : CD3E
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hCD28
- Strain : Repository Live
- KI/KO Gene : CD28
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/Cd8a-IRES-Akaluc-2A-EGFP
- Strain : Embryo cryopres
- KI/KO Gene : Mst1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hPD-L1/hCTLA-4
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hCTLA4(NM-HU-00
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hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c)
- Strain : Developing
- KI/KO Gene : Pdcd1
- Research Application : Humanized Drug
- Nomenclature : BALB/cAnSmoc-Pd
- Description : hSIRPA/hCD47(BA
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hPD-1/hPD-L1(BALB/c)
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Research Application : Humanized Drug
- Nomenclature : BALB/cAnSmoc-Pd
- Description : hPD-1(BALB/c)(N
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hTLR8/hPD-1
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Tlr
- Description : hTLR8(NM-HU-190
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hTNFR2/hIL2RA
- Strain : Embryo cryopres
- KI/KO Gene : IL2RA
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Tnf
- Description : hTNFRSF1B(NM-HU
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