6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine . It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 uM. 6A-8tFP directly competes with protein substrates for the ribosomal active site.
Molecular Formula
C14H9F3N2
Signaling Pathways
Others
Smiles
FC(F)(F)C=1C=CC2=C3C=CC=CC3=NC(N)=C2C1
Cas Number
651055-83-3
Molecular Weight
262.23
Target
Others
Reviews of 6-Amino-8-trifluoromethylphenanthridine