CD121 antigen-like family member A ; Interleukin-1 receptor alpha ; IL-1R-alpha ; Interleukin-1 receptor type I ; p80 ; CD121a ; Il1ra
Categories
Elisa
Function
Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.
Specificity
Natural and recombinant Rat Interleukin-1 receptor type 1