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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Furin

SKU : BHE13804902

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9700r
Alternative Names	Dibasic-processing enzyme ; Paired basic amino acid residue-cleaving enzyme ; PACE ; Prohormone convertase 3 ; Fur ; Pcsk3
Categories	Elisa
Function	Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
Specificity	Natural and recombinant Rat Furin
Subcellular Location	Golgi apparatus trans-Golgi network membrane Single-pass type I membrane protein Cell membrane Single-pass type I membrane protein Shuttles between the trans-Golgi network and the cell surface. Propeptide cleavage is a prerequisite for exit of furin molecules out of the endoplasmic reticulum (ER). A second cleavage within the propeptide occurs in the trans Golgi network (TGN), followed by the release of the propeptide and the activation of furin.
Entryname	FURIN_RAT
Platform	PF01483
Protein Name	Furin
Sequence	50: MELRPWLLWV ; VAAAGALVLL ; AAEARGQKIF ; TNTWAVHISG ; GPAVADSVAR ; 100: KHGFHNLGQI ; FGDYYHFWHR ; AVTKRSLSPH ; RPRHSRLQRV ; PQVKWLEQQV ; 150: AKQRAKRDVY ; QEPTDPKFPQ ; QWYLSGVTQR ; DLNVKEAWAQ ; GFTGRGIVVS ; 200: ILDDGIEKNH ; PDLAGNYDPG ; ASFDVNDQDP ; DPQPRYTQMN ; DNRHGTRCAG ; 250: EVAAVANNGV ; CGVGVAYNAR ; IGGVRMLDGE ; VTDAVEARSL ; GLNPNHIHIY ; 300: SASWGPEDDG ; KTVDGPARLA ; EEAFFRGVSQ ; GRGGLGSIFV ; WASGNGGREH ; 350: DSCNCDGYTN ; SIYTLSISSA ; TQFGNVPWYS ; EACSSTLATT ; YSSGNQNEKQ ; 400: IVTTDLRQKC ; TESHTGTSAS ; APLAAGIIAL ; TLEANKNLTW ; RDMQHLVVQT ; 450: SKPAHLNAND ; WATNGVGRKV ; SHSYGYGLLD ; AGAMVALAQN ; WTTVAPQRKC ; 500: IIEILAEPKD ; IGKRLEVRKT ; VTACLGEPNH ; ISRLEHVQAR ; LTLSYNRRGD ; 550: LAIHLISPMG ; TRSTLLAARP ; HDYSADGFND ; WAFMTTHSWD ; EDPSGEWVLE ; 600: IENTSEANNY ; GTLTKFTLVL ; YGTASEGLSA ; PPESSGCKTL ; TSSQACVVCE ; 650: EGFSLHQKSC ; VQRCPPGFTP ; QVLDTHYSTE ; NDVEIIRASV ; CTPCHASCAT ; 700: CQGPAPTDCL ; SCPSHASLDP ; VEQTCSRQSQ ; SSRESRPQQP ; PPALRPEVEV ; 750: EPRLRAGLAS ; HLPEVLAGLS ; CLIIALIFGI ; VFLFLHRCSG ; FSFRGVKVYT ; 793: MDRGLISYKG ; LPPEAWQEEC ; PSDSEEDEGR ; GERTAFIKDQ ; SAL
Sequence Length	793
String	P23377
Sub Unit	Interacts with FLNA (By similarity). Binds to PACS1 which mediates TGN localization and connection to clathrin adapters.

Uniprot	P23377
Gene Name	Furin
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:54281
Unigene	Rn.3220

Reference	1. "Sequence of the cDNA encoding rat furin, a possible propeptide-processing endoprotease." Misumi Y., Sohoda M., Ikehara Y. Nucleic Acids Res.18:6719-6719(1990) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Wistar. tissue: Liver. 2. "PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization." Wan L., Molloy S.S., Thomas L., Liu G., Xiang Y., Rybak S.L., Thomas G. Cell94:205-216(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PACS1 tissue: Brain.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804902	E9700r	96T	$796		Add to Cart

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